Abstract - Real-time ultrasonography is a non-invasive diagnostic tool used for the diagnosis of pregnancy, fetus quantification and sex determination in animals. Its use in small ruminant’s reproduction is very scanty in Bangladesh. Therefore, we conducted the study to monitor uterine involution in indigenous ewes at the Research Animal Farm, Department of Surgery and Obstetrics, Bangladesh Agricultural University, Bangladesh. After parturition uterine involution was monitored with transabdominal ultrasonography in indigenous ewes. Ultrasonography was performed in nine post-partum indigenous ewes. Daily involution progress was 0.97 ? 0.25 mm from 3rd to sixth day and 0.13 ? 0.04 mm from 15th to 18th day of post- partum. At Day 18, we found iso-echogenic image during ultrasonography of uterine lumen, which indicated that uterus returned to its normal texture. The findings of the study could help the veterinarians to determine superior time for uterus to return into its regular structure during selective breed up-gradation program using giant sheep breed.