Abstract - The present review concentrates on the notion that different blood and blood sera indices play an imperative role in countless biological processes that are significant for reproductive physiology in animals. Specifically, the manuscript describes the necessity of hematological and serum biochemical dynamics in the reproduction of dairy cows. The paper also noticed that reproductive features of dairy cows are disrupted by any digression from the physiologic level of hematological indices including erythrocytes, hemoglobin, platelets and leuko- cytes and serum biochemicals including glucose, protein, lipid profiles and other essential minerals. Thus, researchers could ensure the accurate interpretation of the consequence of haemato-biochemical dynamics in the reproduction of dairy cows.